BindingDB PrimarySearch

BDBM50292296 (E)-2,2,6,6-tetramethyl-4-(3-(5-(4-nitrophenyl)furan-2-yl)acrylamido)piperidin-1-olate::CHEMBL390088

SMILES: CC1(C)CC(CC(C)(C)N1[O])NC(=O)\C=C\c1ccc(o1)-c1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=SEMZZFHBJWNNRZ-ZRDIBKRKSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50292296
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50292296 ((E)-2,2,6,6-tetramethyl-4-(3-(5-(4-nitrophenyl)fur...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of TCPTP				J Med Chem 50: 2137-43 (2007) Article DOI: 10.1021/jm061481l BindingDB Entry DOI: 10.7270/Q2BG2NP4
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM50292296 ((E)-2,2,6,6-tetramethyl-4-(3-(5-(4-nitrophenyl)fur...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of HePTP				J Med Chem 50: 2137-43 (2007) Article DOI: 10.1021/jm061481l BindingDB Entry DOI: 10.7270/Q2BG2NP4
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50292296 ((E)-2,2,6,6-tetramethyl-4-(3-(5-(4-nitrophenyl)fur...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of PTP1B				J Med Chem 50: 2137-43 (2007) Article DOI: 10.1021/jm061481l BindingDB Entry DOI: 10.7270/Q2BG2NP4
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Leukocyte common antigen (Homo sapiens (Human))	BDBM50292296 ((E)-2,2,6,6-tetramethyl-4-(3-(5-(4-nitrophenyl)fur...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of CD45				J Med Chem 50: 2137-43 (2007) Article DOI: 10.1021/jm061481l BindingDB Entry DOI: 10.7270/Q2BG2NP4
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM50292296 ((E)-2,2,6,6-tetramethyl-4-(3-(5-(4-nitrophenyl)fur...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of VHR				J Med Chem 50: 2137-43 (2007) Article DOI: 10.1021/jm061481l BindingDB Entry DOI: 10.7270/Q2BG2NP4
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair