BDBM50292309 CHEMBL4164668

SMILES: FC(F)(F)c1cnc(N2CCN(CC2)C(=O)c2cc(Cl)c[nH]2)c(Cl)c1

InChI Key: InChIKey=WKPUZJTVNPSCNW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292309 (CHEMBL4164668) Show SMILES FC(F)(F)c1cnc(N2CCN(CC2)C(=O)c2cc(Cl)c[nH]2)c(Cl)c1 Show InChI InChI=1S/C15H13Cl2F3N4O/c16-10-6-12(21-8-10)14(25)24-3-1-23(2-4-24)13-11(17)5-9(7-22-13)15(18,19)20/h5-8,21H,1-4H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair