BDBM50292596 CHEMBL522150::{2,4-Dioxo-5-[3-(4-oxo-4H-chromen-2-yl)benzylidene]-1,3-thiazolidine-3yl}acetic acid

SMILES: OC(=O)CN1C(=O)S\C(=C/c2cccc(c2)-c2cc(=O)c3ccccc3o2)C1=O

InChI Key: InChIKey=PUVYYKNRJMKUTH-NVMNQCDNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (Rattus norvegicus)	BDBM50292596 (CHEMBL522150 | {2,4-Dioxo-5-[3-(4-oxo-4H-chromen-2...) Show SMILES OC(=O)CN1C(=O)S\C(=C/c2cccc(c2)-c2cc(=O)c3ccccc3o2)C1=O Show InChI InChI=1S/C21H13NO6S/c23-15-10-17(28-16-7-2-1-6-14(15)16)13-5-3-4-12(8-13)9-18-20(26)22(11-19(24)25)21(27)29-18/h1-10H,11H2,(H,24,25)/b18-9-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	415	n/a	n/a	n/a	n/a	n/a	n/a
Ankara University Curated by ChEMBL					Assay Description Inhibition of rat kidney aldose reductase activity assessed as NADPH oxidation				Bioorg Med Chem 16: 6747-51 (2008) Article DOI: 10.1016/j.bmc.2008.05.059 BindingDB Entry DOI: 10.7270/Q2HT2P4C
					More data for this Ligand-Target Pair