BDBM50292642 (+/-)-1'-(4-bromobenzyl)-3-(pyridin-2-yl)-3,4'-bipiperidine-2,6-dione::CHEMBL496564

SMILES: Brc1ccc(CN2CCC(CC2)C2(CCC(=O)NC2=O)c2ccccn2)cc1

InChI Key: InChIKey=KJOHICOVVWXUGM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50292642 ((+/-)-1'-(4-bromobenzyl)-3-(pyridin-2-yl)-3,4'-bip...) Show SMILES Brc1ccc(CN2CCC(CC2)C2(CCC(=O)NC2=O)c2ccccn2)cc1 Show InChI InChI=1S/C22H24BrN3O2/c23-18-6-4-16(5-7-18)15-26-13-9-17(10-14-26)22(19-3-1-2-12-24-19)11-8-20(27)25-21(22)28/h1-7,12,17H,8-11,13-15H2,(H,25,27,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson PRD Curated by ChEMBL					Assay Description Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...				Bioorg Med Chem Lett 18: 5819-23 (2009) Article DOI: 10.1016/j.bmcl.2008.07.115 BindingDB Entry DOI: 10.7270/Q2RV0NQB
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