BDBM50292697 (1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-(pyridin-3-yl)quinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate::CHEMBL496367

SMILES: CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3cccnc3)cc2)C[C@@H]1C(=O)NO

InChI Key: InChIKey=BDVFOWBSUKDWDA-GIGWZHCTSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50292697 ((1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-(pyrid...) Show SMILES CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3cccnc3)cc2)C[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C29H27N3O5/c1-2-36-28(34)29(16-24(29)27(33)32-35)15-19-9-11-22(12-10-19)37-18-21-14-26(20-6-5-13-30-17-20)31-25-8-4-3-7-23(21)25/h3-14,17,24,35H,2,15-16,18H2,1H3,(H,32,33)/t24-,29+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant TACE				Bioorg Med Chem Lett 18: 5809-14 (2009) Article DOI: 10.1016/j.bmcl.2008.09.045 BindingDB Entry DOI: 10.7270/Q2N29WZX
					More data for this Ligand-Target Pair