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SMILES: COc1cc(NC(=O)\C=C\CN2CCOCC2)cc2c(Nc3cccc(Br)c3)ccnc12

InChI Key: InChIKey=IGFGOGKMSDOPMO-ZZXKWVIFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292737   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50292737
PNG
(CHEMBL472743 | N-(4-(3-bromophenylamino)-8-methoxy...)
Show SMILES COc1cc(NC(=O)\C=C\CN2CCOCC2)cc2c(Nc3cccc(Br)c3)ccnc12
Show InChI InChI=1S/C24H25BrN4O3/c1-31-22-16-19(28-23(30)6-3-9-29-10-12-32-13-11-29)15-20-21(7-8-26-24(20)22)27-18-5-2-4-17(25)14-18/h2-8,14-16H,9-13H2,1H3,(H,26,27)(H,28,30)/b6-3+
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KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.39E+3n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR

J Med Chem 52: 964-75 (2009)


Article DOI: 10.1021/jm800829v
BindingDB Entry DOI: 10.7270/Q27W6C7Q
More data for this
Ligand-Target Pair