BDBM50292754 17beta-Hydroxy-11beta-[4-(N-methylhexylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one::CHEMBL493845

SMILES: CCCCCCN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C12

InChI Key: InChIKey=UHRDSPGREWBOFB-FMHBTXFXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292754   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50292754 (17beta-Hydroxy-11beta-[4-(N-methylhexylamino)-phen...) Show SMILES CCCCCCN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:31,38| Show InChI InChI=1S/C34H45NO2/c1-5-7-8-9-21-35(4)26-13-10-24(11-14-26)30-23-33(3)31(18-20-34(33,37)19-6-2)29-16-12-25-22-27(36)15-17-28(25)32(29)30/h10-11,13-14,22,29-31,37H,5,7-9,12,15-18,20-21,23H2,1-4H3/t29-,30+,31-,33-,34-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
University of Graz Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...				J Med Chem 52: 1268-74 (2010) Article DOI: 10.1021/jm800985z BindingDB Entry DOI: 10.7270/Q27S7PPM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50292754 (17beta-Hydroxy-11beta-[4-(N-methylhexylamino)-phen...) Show SMILES CCCCCCN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:31,38| Show InChI InChI=1S/C34H45NO2/c1-5-7-8-9-21-35(4)26-13-10-24(11-14-26)30-23-33(3)31(18-20-34(33,37)19-6-2)29-16-12-25-22-27(36)15-17-28(25)32(29)30/h10-11,13-14,22,29-31,37H,5,7-9,12,15-18,20-21,23H2,1-4H3/t29-,30+,31-,33-,34-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
University of Graz Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D-C124 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition...				J Med Chem 52: 1268-74 (2010) Article DOI: 10.1021/jm800985z BindingDB Entry DOI: 10.7270/Q27S7PPM
					More data for this Ligand-Target Pair