BindingDB logo
myBDB logout

null

SMILES: COC(=O)CCCCCNC(=O)N(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C12

InChI Key: InChIKey=QQBNYAUHNSUDCD-CGWUTTPTSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292780   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))		BDBM50292780
PNG
(17beta-Hydroxy-11beta-{4-[1-methyl-3-(5-methoxycar...)
Show SMILES COC(=O)CCCCCNC(=O)N(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:37,44|
Show InChI InChI=1S/C36H46N2O5/c1-5-19-36(42)20-18-31-29-16-12-25-22-27(39)15-17-28(25)33(29)30(23-35(31,36)2)24-10-13-26(14-11-24)38(3)34(41)37-21-8-6-7-9-32(40)43-4/h10-11,13-14,22,29-31,42H,6-9,12,15-18,20-21,23H2,1-4H3,(H,37,41)/t29-,30+,31-,35-,36-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.20n/an/an/an/an/an/a



University of Graz

Curated by ChEMBL


Assay Description
Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...

J Med Chem 52: 1268-74 (2010)


Article DOI: 10.1021/jm800985z
BindingDB Entry DOI: 10.7270/Q27S7PPM
More data for this
Ligand-Target Pair