BDBM50292821 4-(2-{1-Benzhydryl-5-chloro-2-[2-({[2-(2-methyl-1-piperidinyl)ethyl]sulfonyl}amino)ethyl]-1H-indol-3-yl}ethoxy)benzoic Acid::CHEMBL501852

SMILES: CC1CCCCN1CCS(=O)(=O)NCCc1c(CCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=UQPGEMRGMILDTH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292821   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50292821 (4-(2-{1-Benzhydryl-5-chloro-2-[2-({[2-(2-methyl-1-...) Show SMILES CC1CCCCN1CCS(=O)(=O)NCCc1c(CCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C40H44ClN3O5S/c1-29-10-8-9-24-43(29)25-27-50(47,48)42-23-21-38-35(22-26-49-34-18-15-32(16-19-34)40(45)46)36-28-33(41)17-20-37(36)44(38)39(30-11-4-2-5-12-30)31-13-6-3-7-14-31/h2-7,11-20,28-29,39,42H,8-10,21-27H2,1H3,(H,45,46)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human cytosolic PLA2alpha by GLU micelle assay				J Med Chem 52: 1156-71 (2009) Article DOI: 10.1021/jm8009876 BindingDB Entry DOI: 10.7270/Q20C4VSK
					More data for this Ligand-Target Pair