BDBM50293038 (R)-N2-(4-Cyanobenzyl)-N1-(4-chlorophenyl)-N2-methylpyrrolidine-1,2-dicarboxamide::CHEMBL462435

SMILES: CN(Cc1ccc(cc1)C#N)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=HUBAFHZHUSREPZ-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50293038 ((R)-N2-(4-Cyanobenzyl)-N1-(4-chlorophenyl)-N2-meth...) Show SMILES CN(Cc1ccc(cc1)C#N)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C21H21ClN4O2/c1-25(14-16-6-4-15(13-23)5-7-16)20(27)19-3-2-12-26(19)21(28)24-18-10-8-17(22)9-11-18/h4-11,19H,2-3,12,14H2,1H3,(H,24,28)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cells				J Med Chem 52: 1295-301 (2010) Article DOI: 10.1021/jm801416q BindingDB Entry DOI: 10.7270/Q25X28Z3
					More data for this Ligand-Target Pair