BDBM50293062 7-{[(1,3-Dihydroxypropan-2-yl)(methyl)amino]methyl]}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL508602

SMILES: CN(Cc1c[nH]c2c1nc[nH]c2=O)C(CO)CO

InChI Key: InChIKey=WWKDGQWJSGDACL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50293062 (7-{[(1,3-Dihydroxypropan-2-yl)(methyl)amino]methyl...) Show SMILES CN(Cc1c[nH]c2c1nc[nH]c2=O)C(CO)CO Show InChI InChI=1S/C11H16N4O3/c1-15(8(4-16)5-17)3-7-2-12-10-9(7)13-6-14-11(10)18/h2,6,8,12,16-17H,3-5H2,1H3,(H,13,14,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Research Limited Curated by ChEMBL					Assay Description Inhibition of human PNP by xanthine-oxidase coupled assay				J Med Chem 52: 1126-43 (2009) Article DOI: 10.1021/jm801421q BindingDB Entry DOI: 10.7270/Q2QR4Z18
					More data for this Ligand-Target Pair