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BDBM50293190 4-cyclopropyl-2-((3-(morpholinomethyl)phenoxy)methyl)morpholine::CHEMBL498626

SMILES: C(Oc1cccc(CN2CCOCC2)c1)C1CN(CCO1)C1CC1

InChI Key: InChIKey=GVKSFFCGUWGTAZ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293190   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50293190
PNG
(4-cyclopropyl-2-((3-(morpholinomethyl)phenoxy)meth...)
Show SMILES C(Oc1cccc(CN2CCOCC2)c1)C1CN(CCO1)C1CC1
Show InChI InChI=1S/C19H28N2O3/c1-2-16(13-20-6-9-22-10-7-20)12-18(3-1)24-15-19-14-21(8-11-23-19)17-4-5-17/h1-3,12,17,19H,4-11,13-15H2
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Article
PubMed
 566n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development L.L.C.

Curated by ChEMBL


Assay Description
Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells

Bioorg Med Chem Lett 18: 5796-9 (2009)


Article DOI: 10.1016/j.bmcl.2008.09.077
BindingDB Entry DOI: 10.7270/Q2154H28
More data for this
Ligand-Target Pair