BDBM50293199 4-cyclopentyl-2-((4-(pyrrolidin-1-ylmethyl)phenoxy)methyl)morpholine::CHEMBL496167

SMILES: C(Oc1ccc(CN2CCCC2)cc1)C1CN(CCO1)C1CCCC1

InChI Key: InChIKey=PBMWBJNBIVVHNL-UHFFFAOYSA-N

Data: 2 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293199 (4-cyclopentyl-2-((4-(pyrrolidin-1-ylmethyl)phenoxy...) Show SMILES C(Oc1ccc(CN2CCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O2/c1-2-6-19(5-1)23-13-14-24-21(16-23)17-25-20-9-7-18(8-10-20)15-22-11-3-4-12-22/h7-10,19,21H,1-6,11-17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293199 (4-cyclopentyl-2-((4-(pyrrolidin-1-ylmethyl)phenoxy...) Show SMILES C(Oc1ccc(CN2CCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O2/c1-2-6-19(5-1)23-13-14-24-21(16-23)17-25-20-9-7-18(8-10-20)15-22-11-3-4-12-22/h7-10,19,21H,1-6,11-17H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293199 (4-cyclopentyl-2-((4-(pyrrolidin-1-ylmethyl)phenoxy...) Show SMILES C(Oc1ccc(CN2CCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O2/c1-2-6-19(5-1)23-13-14-24-21(16-23)17-25-20-9-7-18(8-10-20)15-22-11-3-4-12-22/h7-10,19,21H,1-6,11-17H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.58	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair