BDBM50293262 2-(5-benzyl-2-hydroxyphenyl)-6-methylquinolin-4(1H)-one::CHEMBL502159

SMILES: Cc1ccc2nc(cc(O)c2c1)-c1cc(Cc2ccccc2)ccc1O

InChI Key: InChIKey=ZTLOBJCILUZKRV-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM50293262 (2-(5-benzyl-2-hydroxyphenyl)-6-methylquinolin-4(1H...) Show SMILES Cc1ccc2nc(cc(O)c2c1)-c1cc(Cc2ccccc2)ccc1O Show InChI InChI=1S/C23H19NO2/c1-15-7-9-20-18(11-15)23(26)14-21(24-20)19-13-17(8-10-22(19)25)12-16-5-3-2-4-6-16/h2-11,13-14,25H,12H2,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lund University Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil in rat GABAAalpha1beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 5713-6 (2009) Article DOI: 10.1016/j.bmcl.2008.09.092 BindingDB Entry DOI: 10.7270/Q2CF9Q3Z
					More data for this Ligand-Target Pair
GABA A receptor alpha-5/beta-3/gamma-2 (RAT)	BDBM50293262 (2-(5-benzyl-2-hydroxyphenyl)-6-methylquinolin-4(1H...) Show SMILES Cc1ccc2nc(cc(O)c2c1)-c1cc(Cc2ccccc2)ccc1O Show InChI InChI=1S/C23H19NO2/c1-15-7-9-20-18(11-15)23(26)14-21(24-20)19-13-17(8-10-22(19)25)12-16-5-3-2-4-6-16/h2-11,13-14,25H,12H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lund University Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil in rat GABAAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 5713-6 (2009) Article DOI: 10.1016/j.bmcl.2008.09.092 BindingDB Entry DOI: 10.7270/Q2CF9Q3Z
					More data for this Ligand-Target Pair
GABA(A) receptor subunit alpha-2 (Rattus norvegicus (Rat))	BDBM50293262 (2-(5-benzyl-2-hydroxyphenyl)-6-methylquinolin-4(1H...) Show SMILES Cc1ccc2nc(cc(O)c2c1)-c1cc(Cc2ccccc2)ccc1O Show InChI InChI=1S/C23H19NO2/c1-15-7-9-20-18(11-15)23(26)14-21(24-20)19-13-17(8-10-22(19)25)12-16-5-3-2-4-6-16/h2-11,13-14,25H,12H2,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lund University Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil in rat GABAAalpha2beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 5713-6 (2009) Article DOI: 10.1016/j.bmcl.2008.09.092 BindingDB Entry DOI: 10.7270/Q2CF9Q3Z
					More data for this Ligand-Target Pair
GABA A receptor alpha-3/beta-2/gamma-2 (RAT)	BDBM50293262 (2-(5-benzyl-2-hydroxyphenyl)-6-methylquinolin-4(1H...) Show SMILES Cc1ccc2nc(cc(O)c2c1)-c1cc(Cc2ccccc2)ccc1O Show InChI InChI=1S/C23H19NO2/c1-15-7-9-20-18(11-15)23(26)14-21(24-20)19-13-17(8-10-22(19)25)12-16-5-3-2-4-6-16/h2-11,13-14,25H,12H2,1H3,(H,24,26)	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lund University Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil in rat GABAAalpha3beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 5713-6 (2009) Article DOI: 10.1016/j.bmcl.2008.09.092 BindingDB Entry DOI: 10.7270/Q2CF9Q3Z
					More data for this Ligand-Target Pair