BDBM50293393 (S)-2-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)-N-((6-amino-2-methylpyridin-3-yl)methyl)acetamide, trifluoroacetate::CHEMBL562901

SMILES: CC(=O)N[C@@H]1CSc2ccccc2N(CC(=O)NCc2ccc(N)nc2C)C1=O

InChI Key: InChIKey=XVTNYNFJXKORRC-OAHLLOKOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII/tissue factor (Homo sapiens (Human))	BDBM50293393 ((S)-2-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...) Show SMILES CC(=O)N[C@@H]1CSc2ccccc2N(CC(=O)NCc2ccc(N)nc2C)C1=O |r| Show InChI InChI=1S/C20H23N5O3S/c1-12-14(7-8-18(21)23-12)9-22-19(27)10-25-16-5-3-4-6-17(16)29-11-15(20(25)28)24-13(2)26/h3-8,15H,9-11H2,1-2H3,(H2,21,23)(H,22,27)(H,24,26)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier 1 Curated by ChEMBL					Assay Description Inhibition of human tissue factor/factor 7a				Bioorg Med Chem Lett 19: 1386-91 (2009) Article DOI: 10.1016/j.bmcl.2009.01.039 BindingDB Entry DOI: 10.7270/Q2G73DRB
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50293393 ((S)-2-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...) Show SMILES CC(=O)N[C@@H]1CSc2ccccc2N(CC(=O)NCc2ccc(N)nc2C)C1=O |r| Show InChI InChI=1S/C20H23N5O3S/c1-12-14(7-8-18(21)23-12)9-22-19(27)10-25-16-5-3-4-6-17(16)29-11-15(20(25)28)24-13(2)26/h3-8,15H,9-11H2,1-2H3,(H2,21,23)(H,22,27)(H,24,26)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier 1 Curated by ChEMBL					Assay Description Inhibition of human factor 2a by spectrophotometry				Bioorg Med Chem Lett 19: 1386-91 (2009) Article DOI: 10.1016/j.bmcl.2009.01.039 BindingDB Entry DOI: 10.7270/Q2G73DRB
					More data for this Ligand-Target Pair