BDBM50293394 (R)-N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(3-amino-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)acetamide, bistrifluoroacetate::CHEMBL558275

SMILES: Cc1nc(N)ccc1CNC(=O)CN1c2ccccc2SC[C@H](N)C1=O

InChI Key: InChIKey=UQMQDENIEBTYNQ-ZDUSSCGKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII/tissue factor (Homo sapiens (Human))	BDBM50293394 ((R)-N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(3-...) Show SMILES Cc1nc(N)ccc1CNC(=O)CN1c2ccccc2SC[C@H](N)C1=O |r| Show InChI InChI=1S/C18H21N5O2S/c1-11-12(6-7-16(20)22-11)8-21-17(24)9-23-14-4-2-3-5-15(14)26-10-13(19)18(23)25/h2-7,13H,8-10,19H2,1H3,(H2,20,22)(H,21,24)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier 1 Curated by ChEMBL					Assay Description Inhibition of human tissue factor/factor 7a				Bioorg Med Chem Lett 19: 1386-91 (2009) Article DOI: 10.1016/j.bmcl.2009.01.039 BindingDB Entry DOI: 10.7270/Q2G73DRB
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50293394 ((R)-N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(3-...) Show SMILES Cc1nc(N)ccc1CNC(=O)CN1c2ccccc2SC[C@H](N)C1=O |r| Show InChI InChI=1S/C18H21N5O2S/c1-11-12(6-7-16(20)22-11)8-21-17(24)9-23-14-4-2-3-5-15(14)26-10-13(19)18(23)25/h2-7,13H,8-10,19H2,1H3,(H2,20,22)(H,21,24)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier 1 Curated by ChEMBL					Assay Description Inhibition of human factor 2a by spectrophotometry				Bioorg Med Chem Lett 19: 1386-91 (2009) Article DOI: 10.1016/j.bmcl.2009.01.039 BindingDB Entry DOI: 10.7270/Q2G73DRB
					More data for this Ligand-Target Pair