BDBM50293409 (R)-3-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)-N-(4-carbamimidoylbenzyl)propanamide, trifluoroacetate::CHEMBL554294

SMILES: CC(=O)N[C@H]1CSc2ccccc2N(CCC(=O)NCc2ccc(cc2)C(N)=N)C1=O

InChI Key: InChIKey=WJXOWOUXVFOYQG-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII/tissue factor (Homo sapiens (Human))	BDBM50293409 ((R)-3-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...) Show SMILES CC(=O)N[C@H]1CSc2ccccc2N(CCC(=O)NCc2ccc(cc2)C(N)=N)C1=O |r| Show InChI InChI=1S/C22H25N5O3S/c1-14(28)26-17-13-31-19-5-3-2-4-18(19)27(22(17)30)11-10-20(29)25-12-15-6-8-16(9-7-15)21(23)24/h2-9,17H,10-13H2,1H3,(H3,23,24)(H,25,29)(H,26,28)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.68E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier 1 Curated by ChEMBL					Assay Description Inhibition of human tissue factor/factor 7a				Bioorg Med Chem Lett 19: 1386-91 (2009) Article DOI: 10.1016/j.bmcl.2009.01.039 BindingDB Entry DOI: 10.7270/Q2G73DRB
					More data for this Ligand-Target Pair