null

SMILES: Cc1csc(n1)-c1nc(Nc2ccncc2)c2ccccc2n1

InChI Key: InChIKey=NBMFKJACAZPWPF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50293515 (2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazoli...) Show SMILES Cc1csc(n1)-c1nc(Nc2ccncc2)c2ccccc2n1 Show InChI InChI=1S/C17H13N5S/c1-11-10-23-17(19-11)16-21-14-5-3-2-4-13(14)15(22-16)20-12-6-8-18-9-7-12/h2-10H,1H3,(H,18,20,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human ALK5 kinase expressed in Sf9 cells				Bioorg Med Chem Lett 19: 2277-81 (2009) Article DOI: 10.1016/j.bmcl.2009.02.087 BindingDB Entry DOI: 10.7270/Q2K07497
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50293515 (2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazoli...) Show SMILES Cc1csc(n1)-c1nc(Nc2ccncc2)c2ccccc2n1 Show InChI InChI=1S/C17H13N5S/c1-11-10-23-17(19-11)16-21-14-5-3-2-4-13(14)15(22-16)20-12-6-8-18-9-7-12/h2-10H,1H3,(H,18,20,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	342	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assay				Bioorg Med Chem Lett 19: 2277-81 (2009) Article DOI: 10.1016/j.bmcl.2009.02.087 BindingDB Entry DOI: 10.7270/Q2K07497
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50293515 (2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazoli...) Show SMILES Cc1csc(n1)-c1nc(Nc2ccncc2)c2ccccc2n1 Show InChI InChI=1S/C17H13N5S/c1-11-10-23-17(19-11)16-21-14-5-3-2-4-13(14)15(22-16)20-12-6-8-18-9-7-12/h2-10H,1H3,(H,18,20,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-fused p38alpha				Bioorg Med Chem Lett 19: 2277-81 (2009) Article DOI: 10.1016/j.bmcl.2009.02.087 BindingDB Entry DOI: 10.7270/Q2K07497
					More data for this Ligand-Target Pair