BDBM50293746 1-(1-phenylcyclopropyl)-2-(4-sulfamoylphenylamino)-1H-benzo[d]imidazole-5-carboxamide::CHEMBL554935

SMILES: NC(=O)c1ccc2n(c(Nc3ccc(cc3)S(N)(=O)=O)nc2c1)C1(CC1)c1ccccc1

InChI Key: InChIKey=CXPSJOTWGOTXOU-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293746   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50293746 (1-(1-phenylcyclopropyl)-2-(4-sulfamoylphenylamino)...) Show SMILES NC(=O)c1ccc2n(c(Nc3ccc(cc3)S(N)(=O)=O)nc2c1)C1(CC1)c1ccccc1 Show InChI InChI=1S/C23H21N5O3S/c24-21(29)15-6-11-20-19(14-15)27-22(26-17-7-9-18(10-8-17)32(25,30)31)28(20)23(12-13-23)16-4-2-1-3-5-16/h1-11,14H,12-13H2,(H2,24,29)(H,26,27)(H2,25,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human kinesin spindle protein by endpoint assay				Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3
					More data for this Ligand-Target Pair
Kinesin heavy chain isoform 5A (Homo sapiens (Human))	BDBM50293746 (1-(1-phenylcyclopropyl)-2-(4-sulfamoylphenylamino)...) Show SMILES NC(=O)c1ccc2n(c(Nc3ccc(cc3)S(N)(=O)=O)nc2c1)C1(CC1)c1ccccc1 Show InChI InChI=1S/C23H21N5O3S/c24-21(29)15-6-11-20-19(14-15)27-22(26-17-7-9-18(10-8-17)32(25,30)31)28(20)23(12-13-23)16-4-2-1-3-5-16/h1-11,14H,12-13H2,(H2,24,29)(H,26,27)(H2,25,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of nKHC				Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3
					More data for this Ligand-Target Pair
Kinesin-like protein KIF3B (Homo sapiens (Human))	BDBM50293746 (1-(1-phenylcyclopropyl)-2-(4-sulfamoylphenylamino)...) Show SMILES NC(=O)c1ccc2n(c(Nc3ccc(cc3)S(N)(=O)=O)nc2c1)C1(CC1)c1ccccc1 Show InChI InChI=1S/C23H21N5O3S/c24-21(29)15-6-11-20-19(14-15)27-22(26-17-7-9-18(10-8-17)32(25,30)31)28(20)23(12-13-23)16-4-2-1-3-5-16/h1-11,14H,12-13H2,(H2,24,29)(H,26,27)(H2,25,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Kif3B				Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3
					More data for this Ligand-Target Pair