BDBM50293831 (S)-(1-(5-amino-7-oxo-1,2,6,7-tetrahydro-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)propan-2-yloxy)methylphosphonate::CHEMBL561353

SMILES: C[C@@H](CN1NNc2c1nc(N)[nH]c2=O)OCP(O)(O)=O

InChI Key: InChIKey=QUUFIELQBMFQPQ-BYPYZUCNSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50293831 ((S)-(1-(5-amino-7-oxo-1,2,6,7-tetrahydro-[1,2,3]tr...) Show SMILES C[C@@H](CN1NNc2c1nc(N)[nH]c2=O)OCP(O)(O)=O |r| Show InChI InChI=1S/C8H15N6O5P/c1-4(19-3-20(16,17)18)2-14-6-5(12-13-14)7(15)11-8(9)10-6/h4,12-13H,2-3H2,1H3,(H2,16,17,18)(H3,9,10,11,15)/t4-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assay				J Med Chem 52: 4391-9 (2009) Article DOI: 10.1021/jm900267n BindingDB Entry DOI: 10.7270/Q27M0809
					More data for this Ligand-Target Pair