BDBM50293838 (2-(6-oxo-1,6,7,8-tetrahydropurin-9-yl)ethoxy)methylphosphonate::CHEMBL564977

SMILES: OP(O)(=O)COCCN1CNc2c1nc[nH]c2=O

InChI Key: InChIKey=YMOJWLJEHWMICS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50293838 ((2-(6-oxo-1,6,7,8-tetrahydropurin-9-yl)ethoxy)meth...) Show SMILES OP(O)(=O)COCCN1CNc2c1nc[nH]c2=O Show InChI InChI=1S/C8H13N4O5P/c13-8-6-7(9-3-10-8)12(4-11-6)1-2-17-5-18(14,15)16/h3,11H,1-2,4-5H2,(H,9,10,13)(H2,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.82E+5	n/a	n/a	n/a	n/a	n/a	n/a	8.5	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human recombinant HGPRT at pH 8.5 by spectrophotometric assay				J Med Chem 52: 4391-9 (2009) Article DOI: 10.1021/jm900267n BindingDB Entry DOI: 10.7270/Q27M0809
					More data for this Ligand-Target Pair