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SMILES: Cc1cc(-c2cscn2)c2cccc(OCc3c(Cl)cncc3Cl)c2n1

InChI Key: InChIKey=GEKUROOQGKKPSR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50293876 (8-(3,5-dichloro-pyridin-4-ylmethoxy)-2-methyl-4-th...) Show SMILES Cc1cc(-c2cscn2)c2cccc(OCc3c(Cl)cncc3Cl)c2n1 Show InChI InChI=1S/C19H13Cl2N3OS/c1-11-5-13(17-9-26-10-23-17)12-3-2-4-18(19(12)24-11)25-8-14-15(20)6-22-7-16(14)21/h2-7,9-10H,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Jerini AG Curated by ChEMBL					Assay Description Displacement of [3H]bradykinin from human recombinant B2 receptor expressed in HEK293 cells				J Med Chem 52: 4370-9 (2009) Article DOI: 10.1021/jm9002445 BindingDB Entry DOI: 10.7270/Q2KS6RKT
					More data for this Ligand-Target Pair
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50293876 (8-(3,5-dichloro-pyridin-4-ylmethoxy)-2-methyl-4-th...) Show SMILES Cc1cc(-c2cscn2)c2cccc(OCc3c(Cl)cncc3Cl)c2n1 Show InChI InChI=1S/C19H13Cl2N3OS/c1-11-5-13(17-9-26-10-23-17)12-3-2-4-18(19(12)24-11)25-8-14-15(20)6-22-7-16(14)21/h2-7,9-10H,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Jerini AG Curated by ChEMBL					Assay Description Antagonist activity at B2 receptor in human HF15 cells assessed as inhibition of bradykinin-induced calcium mobilization				J Med Chem 52: 4370-9 (2009) Article DOI: 10.1021/jm9002445 BindingDB Entry DOI: 10.7270/Q2KS6RKT
					More data for this Ligand-Target Pair