BDBM50293954 5-Chloro-3-(4-methoxy-2,5-dimethylphenylamino)-1-[2-methoxy-1-(methoxymethyl)ethyl]pyrazin-2(1H)-one::CHEMBL572347

SMILES: COCC(COC)n1cc(Cl)nc(Nc2cc(C)c(OC)cc2C)c1=O

InChI Key: InChIKey=REFXTPVTKVNEPN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor (Rattus norvegicus (rat))	BDBM50293954 (5-Chloro-3-(4-methoxy-2,5-dimethylphenylamino)-1-[...) Show SMILES COCC(COC)n1cc(Cl)nc(Nc2cc(C)c(OC)cc2C)c1=O Show InChI InChI=1S/C18H24ClN3O4/c1-11-7-15(26-5)12(2)6-14(11)20-17-18(23)22(8-16(19)21-17)13(9-24-3)10-25-4/h6-8,13H,9-10H2,1-5H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma counting				J Med Chem 52: 4173-91 (2009) Article DOI: 10.1021/jm900301y BindingDB Entry DOI: 10.7270/Q2G44Q9K
					More data for this Ligand-Target Pair