BDBM50294017 CHEMBL549940::N-(2-fluorobenzylidene)(4-sulfonamidephenyl)ethanamine

SMILES: NS(=O)(=O)c1ccc(CC\N=C\c2ccccc2F)cc1

InChI Key: InChIKey=DJUPOFLPZNEZRV-WOJGMQOQSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294017   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50294017 (CHEMBL549940 | N-(2-fluorobenzylidene)(4-sulfonami...) Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2ccccc2F)cc1 Show InChI InChI=1S/C15H15FN2O2S/c16-15-4-2-1-3-13(15)11-18-10-9-12-5-7-14(8-6-12)21(17,19)20/h1-8,11H,9-10H2,(H2,17,19,20)/b18-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCM/UMII/UMR-CNRS 5635 Curated by ChEMBL					Assay Description Inhibition of human erythrocytes carbonic anhydrase 2 by CO2 hydration assay				J Med Chem 52: 4853-9 (2009) Article DOI: 10.1021/jm900449v BindingDB Entry DOI: 10.7270/Q26M36VH
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50294017 (CHEMBL549940 | N-(2-fluorobenzylidene)(4-sulfonami...) Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2ccccc2F)cc1 Show InChI InChI=1S/C15H15FN2O2S/c16-15-4-2-1-3-13(15)11-18-10-9-12-5-7-14(8-6-12)21(17,19)20/h1-8,11H,9-10H2,(H2,17,19,20)/b18-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCM/UMII/UMR-CNRS 5635 Curated by ChEMBL					Assay Description Inhibition of human erythrocytes carbonic anhydrase 1 by CO2 hydration assay				J Med Chem 52: 4853-9 (2009) Article DOI: 10.1021/jm900449v BindingDB Entry DOI: 10.7270/Q26M36VH
					More data for this Ligand-Target Pair