BDBM50294052 2-[(1-Pyrrolidinylcarbonyl)amino]benzoic Acid::CHEMBL539925

SMILES: OC(=O)c1ccccc1NC(=O)N1CCCC1

InChI Key: InChIKey=QAOIGTCTZRIIDN-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Multidrug resistance protein 1/Multidrug resistance associated protein 1 (Homo sapiens (Human))	BDBM50294052 (2-[(1-Pyrrolidinylcarbonyl)amino]benzoic Acid | CH...) Show SMILES OC(=O)c1ccccc1NC(=O)N1CCCC1 Show InChI InChI=1S/C12H14N2O3/c15-11(16)9-5-1-2-6-10(9)13-12(17)14-7-3-4-8-14/h1-2,5-6H,3-4,7-8H2,(H,13,17)(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
					More data for this Ligand-Target Pair