Found 4 hits for monomerid = 50294258 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50294258
(CHEMBL541226 | rac-4-((2,3-dichlorophenoxy)(phenyl...)Show InChI InChI=1S/C18H19Cl2NO/c19-15-7-4-8-16(17(15)20)22-18(13-5-2-1-3-6-13)14-9-11-21-12-10-14/h1-8,14,18,21H,9-12H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2829-34 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50294258
(CHEMBL541226 | rac-4-((2,3-dichlorophenoxy)(phenyl...)Show InChI InChI=1S/C18H19Cl2NO/c19-15-7-4-8-16(17(15)20)22-18(13-5-2-1-3-6-13)14-9-11-21-12-10-14/h1-8,14,18,21H,9-12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human ERG channel |
Bioorg Med Chem Lett 19: 2829-34 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50294258
(CHEMBL541226 | rac-4-((2,3-dichlorophenoxy)(phenyl...)Show InChI InChI=1S/C18H19Cl2NO/c19-15-7-4-8-16(17(15)20)22-18(13-5-2-1-3-6-13)14-9-11-21-12-10-14/h1-8,14,18,21H,9-12H2 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of [3H]DA uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2829-34 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50294258
(CHEMBL541226 | rac-4-((2,3-dichlorophenoxy)(phenyl...)Show InChI InChI=1S/C18H19Cl2NO/c19-15-7-4-8-16(17(15)20)22-18(13-5-2-1-3-6-13)14-9-11-21-12-10-14/h1-8,14,18,21H,9-12H2 | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of [3H]NA uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2829-34 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX |
More data for this Ligand-Target Pair | |