BDBM50294262 CHEMBL551556::rac-3-(piperidin-4-yl(2-(trifluoromethyl)phenoxy)methyl)pyridine

SMILES: FC(F)(F)c1ccccc1OC(C1CCNCC1)c1cccnc1

InChI Key: InChIKey=ABLMTRUAAOJKSC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50294262 (CHEMBL551556 | rac-3-(piperidin-4-yl(2-(trifluorom...) Show SMILES FC(F)(F)c1ccccc1OC(C1CCNCC1)c1cccnc1 Show InChI InChI=1S/C18H19F3N2O/c19-18(20,21)15-5-1-2-6-16(15)24-17(13-7-10-22-11-8-13)14-4-3-9-23-12-14/h1-6,9,12-13,17,22H,7-8,10-11H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50294262 (CHEMBL551556 | rac-3-(piperidin-4-yl(2-(trifluorom...) Show SMILES FC(F)(F)c1ccccc1OC(C1CCNCC1)c1cccnc1 Show InChI InChI=1S/C18H19F3N2O/c19-18(20,21)15-5-1-2-6-16(15)24-17(13-7-10-22-11-8-13)14-4-3-9-23-12-14/h1-6,9,12-13,17,22H,7-8,10-11H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]NA uptake at human NET expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX
					More data for this Ligand-Target Pair