BDBM50294278 CHEMBL563404::rac2-((biphenyl-2-yloxy)(piperidin-4-yl)methyl)pyridine

SMILES: C1CC(CCN1)C(Oc1ccccc1-c1ccccc1)c1ccccn1

InChI Key: InChIKey=GNYXJFDSZWNBKT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50294278 (CHEMBL563404 | rac2-((biphenyl-2-yloxy)(piperidin-...) Show SMILES C1CC(CCN1)C(Oc1ccccc1-c1ccccc1)c1ccccn1 Show InChI InChI=1S/C23H24N2O/c1-2-8-18(9-3-1)20-10-4-5-12-22(20)26-23(19-13-16-24-17-14-19)21-11-6-7-15-25-21/h1-12,15,19,23-24H,13-14,16-17H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50294278 (CHEMBL563404 | rac2-((biphenyl-2-yloxy)(piperidin-...) Show SMILES C1CC(CCN1)C(Oc1ccccc1-c1ccccc1)c1ccccn1 Show InChI InChI=1S/C23H24N2O/c1-2-8-18(9-3-1)20-10-4-5-12-22(20)26-23(19-13-16-24-17-14-19)21-11-6-7-15-25-21/h1-12,15,19,23-24H,13-14,16-17H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]NA uptake at human NET expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX
					More data for this Ligand-Target Pair