BDBM50294280 CHEMBL560050::rac-2-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-3-methylpyridine

SMILES: Cc1cccnc1C(Oc1cccc(Cl)c1Cl)C1CCNCC1

InChI Key: InChIKey=ICZPNJDXXLLJEO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50294280 (CHEMBL560050 | rac-2-((2,3-dichlorophenoxy)(piperi...) Show SMILES Cc1cccnc1C(Oc1cccc(Cl)c1Cl)C1CCNCC1 Show InChI InChI=1S/C18H20Cl2N2O/c1-12-4-3-9-22-17(12)18(13-7-10-21-11-8-13)23-15-6-2-5-14(19)16(15)20/h2-6,9,13,18,21H,7-8,10-11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50294280 (CHEMBL560050 | rac-2-((2,3-dichlorophenoxy)(piperi...) Show SMILES Cc1cccnc1C(Oc1cccc(Cl)c1Cl)C1CCNCC1 Show InChI InChI=1S/C18H20Cl2N2O/c1-12-4-3-9-22-17(12)18(13-7-10-21-11-8-13)23-15-6-2-5-14(19)16(15)20/h2-6,9,13,18,21H,7-8,10-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]NA uptake at human NET expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2829-34 (2009) Article DOI: 10.1016/j.bmcl.2009.03.090 BindingDB Entry DOI: 10.7270/Q2HX1CQX
					More data for this Ligand-Target Pair