BDBM50294466 3-(4-fluorophenylthio)-6-(4-methyl-4H-1,2,4-triazol-3-ylthio)-N-(thiazol-2-yl)picolinamide::CHEMBL564110

SMILES: Cn1cnnc1Sc1ccc(Sc2ccc(F)cc2)c(n1)C(=O)Nc1nccs1

InChI Key: InChIKey=YIYCQXYPCZMPSG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hexokinase-4 (Homo sapiens (Human))	BDBM50294466 (3-(4-fluorophenylthio)-6-(4-methyl-4H-1,2,4-triazo...) Show SMILES Cn1cnnc1Sc1ccc(Sc2ccc(F)cc2)c(n1)C(=O)Nc1nccs1 Show InChI InChI=1S/C18H13FN6OS3/c1-25-10-21-24-18(25)29-14-7-6-13(28-12-4-2-11(19)3-5-12)15(22-14)16(26)23-17-20-8-9-27-17/h2-10H,1H3,(H,20,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Activation of glucokinase				Bioorg Med Chem Lett 19: 2718-21 (2009) Article DOI: 10.1016/j.bmcl.2009.03.137 BindingDB Entry DOI: 10.7270/Q24M94J9
					More data for this Ligand-Target Pair