BDBM50294522 2-amino-6-(furan-2-yl)-N-(pyridin-4-ylmethyl)pyrimidine-4-carboxamide::CHEMBL564142
SMILES: Nc1nc(cc(n1)-c1ccco1)C(=O)NCc1ccncc1
InChI Key: InChIKey=OVPOEJWCXDGJTP-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50294522 (2-amino-6-(furan-2-yl)-N-(pyridin-4-ylmethyl)pyrim...) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 388 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R+D) Ltd. Curated by ChEMBL | Assay Description Displacement of [3H]CGS21680 from human adenosine A2A receptor | Bioorg Med Chem Lett 19: 2664-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.142 BindingDB Entry DOI: 10.7270/Q2RF5V1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50294522 (2-amino-6-(furan-2-yl)-N-(pyridin-4-ylmethyl)pyrim...) | PDB Reactome pathway KEGG DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R+D) Ltd. Curated by ChEMBL | Assay Description Displacement of [3H]CGS21680 from human adenosine A1 receptor | Bioorg Med Chem Lett 19: 2664-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.142 BindingDB Entry DOI: 10.7270/Q2RF5V1M | |||||||||||
More data for this Ligand-Target Pair |