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SMILES: Nc1ccccc1-c1nnc(o1)C(=O)NCc1cccc2nsnc12

InChI Key: InChIKey=UPJYVJFPLZSUIS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295132   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cruzipain


(Trypanosoma cruzi)		BDBM50295132
PNG
(5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic ...)
Show SMILES Nc1ccccc1-c1nnc(o1)C(=O)NCc1cccc2nsnc12
Show InChI InChI=1S/C16H12N6O2S/c17-11-6-2-1-5-10(11)15-19-20-16(24-15)14(23)18-8-9-4-3-7-12-13(9)22-25-21-12/h1-7H,8,17H2,(H,18,23)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi cruzain preincubated for 5 mins before substrate addition

J Med Chem 52: 5005-8 (2010)


Article DOI: 10.1021/jm9009229
BindingDB Entry DOI: 10.7270/Q24J0F50
More data for this
Ligand-Target Pair