BDBM50295187 2-p-tolylpyrazolo[1,5-a]quinazolin-5(4H)-one::CHEMBL550370

SMILES: Cc1ccc(cc1)-c1cc2[nH]c(=O)c3ccccc3n2n1

InChI Key: InChIKey=YZYXTSIMDPDOTA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50295187 (2-p-tolylpyrazolo[1,5-a]quinazolin-5(4H)-one | CHE...) Show SMILES Cc1ccc(cc1)-c1cc2[nH]c(=O)c3ccccc3n2n1 Show InChI InChI=1S/C17H13N3O/c1-11-6-8-12(9-7-11)14-10-16-18-17(21)13-4-2-3-5-15(13)20(16)19-14/h2-10H,1H3,(H,18,21)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
IRBM - Merck Research Laboratories Rome Curated by ChEMBL					Assay Description Inhibition of PARP1 by scintillation proximity assay				Bioorg Med Chem Lett 19: 4196-200 (2009) Article DOI: 10.1016/j.bmcl.2009.05.113 BindingDB Entry DOI: 10.7270/Q2MG7PHP
					More data for this Ligand-Target Pair