BDBM50295202 4-(5-oxo-4,5-dihydropyrazolo[1,5-a]quinazolin-2-yl)benzonitrile::CHEMBL550384

SMILES: O=c1[nH]c2cc(nn2c2ccccc12)-c1ccc(cc1)C#N

InChI Key: InChIKey=YDRQYGUVONIMTQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50295202 (4-(5-oxo-4,5-dihydropyrazolo[1,5-a]quinazolin-2-yl...) Show SMILES O=c1[nH]c2cc(nn2c2ccccc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C17H10N4O/c18-10-11-5-7-12(8-6-11)14-9-16-19-17(22)13-3-1-2-4-15(13)21(16)20-14/h1-9H,(H,19,22)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
IRBM - Merck Research Laboratories Rome Curated by ChEMBL					Assay Description Inhibition of PARP1 by scintillation proximity assay				Bioorg Med Chem Lett 19: 4196-200 (2009) Article DOI: 10.1016/j.bmcl.2009.05.113 BindingDB Entry DOI: 10.7270/Q2MG7PHP
					More data for this Ligand-Target Pair