BDBM50295211 2-phenylpyrazolo[1,5-a]quinazolin-5(4H)-one::CHEMBL571223

SMILES: O=c1[nH]c2cc(nn2c2ccccc12)-c1ccccc1

InChI Key: InChIKey=PBGUSECSIDSSHI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50295211 (2-phenylpyrazolo[1,5-a]quinazolin-5(4H)-one | CHEM...) Show SMILES O=c1[nH]c2cc(nn2c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C16H11N3O/c20-16-12-8-4-5-9-14(12)19-15(17-16)10-13(18-19)11-6-2-1-3-7-11/h1-10H,(H,17,20)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
IRBM - Merck Research Laboratories Rome Curated by ChEMBL					Assay Description Inhibition of PARP1 by scintillation proximity assay				Bioorg Med Chem Lett 19: 4196-200 (2009) Article DOI: 10.1016/j.bmcl.2009.05.113 BindingDB Entry DOI: 10.7270/Q2MG7PHP
					More data for this Ligand-Target Pair