BDBM50295213 CHEMBL550501::N-(2-(dimethylamino)ethyl)-N-methyl-5-oxo-4,5-dihydropyrazolo[1,5-a]quinazoline-2-carboxamide

SMILES: CN(C)CCN(C)C(=O)c1cc2[nH]c(=O)c3ccccc3n2n1

InChI Key: InChIKey=MWYHTQGJBUIJQS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50295213 (CHEMBL550501 | N-(2-(dimethylamino)ethyl)-N-methyl...) Show SMILES CN(C)CCN(C)C(=O)c1cc2[nH]c(=O)c3ccccc3n2n1 Show InChI InChI=1S/C16H19N5O2/c1-19(2)8-9-20(3)16(23)12-10-14-17-15(22)11-6-4-5-7-13(11)21(14)18-12/h4-7,10H,8-9H2,1-3H3,(H,17,22)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
IRBM - Merck Research Laboratories Rome Curated by ChEMBL					Assay Description Inhibition of PARP1 by scintillation proximity assay				Bioorg Med Chem Lett 19: 4196-200 (2009) Article DOI: 10.1016/j.bmcl.2009.05.113 BindingDB Entry DOI: 10.7270/Q2MG7PHP
					More data for this Ligand-Target Pair