BDBM50295217 2-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]quinazolin-5(4H)-one::CHEMBL562117

SMILES: COc1cc(cc(OC)c1OC)-c1cc2[nH]c(=O)c3ccccc3n2n1

InChI Key: InChIKey=SMPCVIKAYTYWTL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50295217 (2-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]quinazoli...) Show SMILES COc1cc(cc(OC)c1OC)-c1cc2[nH]c(=O)c3ccccc3n2n1 Show InChI InChI=1S/C19H17N3O4/c1-24-15-8-11(9-16(25-2)18(15)26-3)13-10-17-20-19(23)12-6-4-5-7-14(12)22(17)21-13/h4-10H,1-3H3,(H,20,23)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
IRBM - Merck Research Laboratories Rome Curated by ChEMBL					Assay Description Inhibition of PARP1 by scintillation proximity assay				Bioorg Med Chem Lett 19: 4196-200 (2009) Article DOI: 10.1016/j.bmcl.2009.05.113 BindingDB Entry DOI: 10.7270/Q2MG7PHP
					More data for this Ligand-Target Pair