BDBM50295227 11-(2-chloro-6-fluorophenyl)-3-(4-methoxyphenyl)-8-methyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one::CHEMBL552257

SMILES: COc1ccc(cc1)C1CC(=O)C2C(Nc3cc(C)ccc3N=C2C1)c1c(F)cccc1Cl

InChI Key: InChIKey=NEKFODSJSXDKOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295227   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NMBR (Homo sapiens (Human))	BDBM50295227 (11-(2-chloro-6-fluorophenyl)-3-(4-methoxyphenyl)-8...) Show SMILES COc1ccc(cc1)C1CC(=O)C2C(Nc3cc(C)ccc3N=C2C1)c1c(F)cccc1Cl |c:24| Show InChI InChI=1S/C27H24ClFN2O2/c1-15-6-11-21-22(12-15)31-27(25-19(28)4-3-5-20(25)29)26-23(30-21)13-17(14-24(26)32)16-7-9-18(33-2)10-8-16/h3-12,17,26-27,31H,13-14H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cells				Bioorg Med Chem Lett 19: 4264-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.124 BindingDB Entry DOI: 10.7270/Q2C24WG8
					More data for this Ligand-Target Pair