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BDBM50295229 11-(2-chloro-6-fluorophenyl)-3-(4-(dimethylamino)phenyl)-8-methyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one::CHEMBL551917

SMILES: CN(C)c1ccc(cc1)C1CC(=O)C2C(Nc3cc(C)ccc3N=C2C1)c1c(F)cccc1Cl

InChI Key: InChIKey=UZLDKHSRWXTDED-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295229   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NMBR


(Homo sapiens (Human))		BDBM50295229
PNG
(11-(2-chloro-6-fluorophenyl)-3-(4-(dimethylamino)p...)
Show SMILES CN(C)c1ccc(cc1)C1CC(=O)C2C(Nc3cc(C)ccc3N=C2C1)c1c(F)cccc1Cl |c:25|
Show InChI InChI=1S/C28H27ClFN3O/c1-16-7-12-22-23(13-16)32-28(26-20(29)5-4-6-21(26)30)27-24(31-22)14-18(15-25(27)34)17-8-10-19(11-9-17)33(2)3/h4-13,18,27-28,32H,14-15H2,1-3H3
KEGG

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Similars
Article
PubMed
n/an/a 5.40E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cells

Bioorg Med Chem Lett 19: 4264-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.124
BindingDB Entry DOI: 10.7270/Q2C24WG8
More data for this
Ligand-Target Pair