BDBM50295253 11-(2-chloro-6-fluorophenyl)-3,3,5,8-tetramethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one::CHEMBL551511

SMILES: CN1C2=C(C(Nc3cc(C)ccc13)c1c(F)cccc1Cl)C(=O)CC(C)(C)C2

InChI Key: InChIKey=GJUAHVLWKLUKCV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NMBR (Homo sapiens (Human))	BDBM50295253 (11-(2-chloro-6-fluorophenyl)-3,3,5,8-tetramethyl-2...) Show SMILES CN1C2=C(C(Nc3cc(C)ccc13)c1c(F)cccc1Cl)C(=O)CC(C)(C)C2 |c:2| Show InChI InChI=1S/C23H24ClFN2O/c1-13-8-9-17-16(10-13)26-22(20-14(24)6-5-7-15(20)25)21-18(27(17)4)11-23(2,3)12-19(21)28/h5-10,22,26H,11-12H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cells				Bioorg Med Chem Lett 19: 4264-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.124 BindingDB Entry DOI: 10.7270/Q2C24WG8
					More data for this Ligand-Target Pair