BDBM50295442 CHEMBL3084635::Exo-8-[bis(2-chlorophenyl)methyl]-3-(4-methyl-2-pyridinyl)-8-azabicyclo[3.2.1]octane

SMILES: [H][C@]12CC[C@]([H])(C[C@@H](C1)c1cc(C)ccn1)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key: InChIKey=SDIJRCLRWUUJRW-PMACEKPBSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50295442 (CHEMBL3084635 | Exo-8-[bis(2-chlorophenyl)methyl]-...) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)c1cc(C)ccn1)N2C(c1ccccc1Cl)c1ccccc1Cl |r,TLB:9:7:16:2.3| Show InChI InChI=1S/C26H26Cl2N2/c1-17-12-13-29-25(14-17)18-15-19-10-11-20(16-18)30(19)26(21-6-2-4-8-23(21)27)22-7-3-5-9-24(22)28/h2-9,12-14,18-20,26H,10-11,15-16H2,1H3/t19-,20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr14-N/OFQ from human NOP receptor expressed in CHO cells by Topcount microplate scintillation counting				J Med Chem 52: 5323-9 (2009) Article DOI: 10.1021/jm9008218 BindingDB Entry DOI: 10.7270/Q2DV1JX2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50295442 (CHEMBL3084635 | Exo-8-[bis(2-chlorophenyl)methyl]-...) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)c1cc(C)ccn1)N2C(c1ccccc1Cl)c1ccccc1Cl |r,TLB:9:7:16:2.3| Show InChI InChI=1S/C26H26Cl2N2/c1-17-12-13-29-25(14-17)18-15-19-10-11-20(16-18)30(19)26(21-6-2-4-8-23(21)27)22-7-3-5-9-24(22)28/h2-9,12-14,18-20,26H,10-11,15-16H2,1H3/t19-,20-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	891	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells by Topcount microplate scintillation counting				J Med Chem 52: 5323-9 (2009) Article DOI: 10.1021/jm9008218 BindingDB Entry DOI: 10.7270/Q2DV1JX2
					More data for this Ligand-Target Pair