BDBM50295453 1-Acetyl-2-[exo-8-[bis(2-chlorophenyl)methyl]-8-azabicyclo[3.2.1]-oct-3-yl]piperidine::CHEMBL551454

SMILES: CC(=O)N1CCCCC1C1C[C@@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key: InChIKey=ZOKXPVBKMFHHNR-IPEYFGQDSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50295453 (1-Acetyl-2-[exo-8-[bis(2-chlorophenyl)methyl]-8-az...) Show SMILES CC(=O)N1CCCCC1C1C[C@@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl |r,TLB:8:9:16:12.13,17:16:9.10.15:12.13| Show InChI InChI=1S/C27H32Cl2N2O/c1-18(32)30-15-7-6-12-26(30)19-16-20-13-14-21(17-19)31(20)27(22-8-2-4-10-24(22)28)23-9-3-5-11-25(23)29/h2-5,8-11,19-21,26-27H,6-7,12-17H2,1H3/t20-,21-,26?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr14-N/OFQ from human NOP receptor expressed in CHO cells by Topcount microplate scintillation counting				J Med Chem 52: 5323-9 (2009) Article DOI: 10.1021/jm9008218 BindingDB Entry DOI: 10.7270/Q2DV1JX2
					More data for this Ligand-Target Pair