Found 6 hits for monomerid = 50295572 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-adrenergic receptor kinase 1
(Homo sapiens (Human)) | BDBM50295572
(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8/h3-5,7,11-15H,6H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a |
Merck, Sharp, and Dohme Research Laboratories
| Assay Description The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP. |
J Biol Chem 264: 13572-8 (1989)
BindingDB Entry DOI: 10.7270/Q29G5KDJ |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50295572
(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8/h3-5,7,11-15H,6H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | n/a | 4.81E+3 | n/a | n/a | n/a | n/a | n/a |
Instituto Polit£cnico Nacional
Curated by ChEMBL
| Assay Description Binding affinity to human adrenergic beta2 receptor |
Eur J Med Chem 44: 2840-6 (2009)
Article DOI: 10.1016/j.ejmech.2008.12.016 BindingDB Entry DOI: 10.7270/Q2FQ9XJN |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50295572
(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8/h3-5,7,11-15H,6H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina
Curated by ChEMBL
| Assay Description Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nM |
Bioorg Med Chem Lett 23: 5376-81 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.052 BindingDB Entry DOI: 10.7270/Q2F76GHV |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(BOVINE) | BDBM50295572
(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8/h3-5,7,11-15H,6H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | 4.27E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA) |
J Med Chem 28: 1328-34 (1985)
BindingDB Entry DOI: 10.7270/Q2HX1DZG |
More data for this Ligand-Target Pair | |
Bile salt export pump
(Homo sapiens (Human)) | BDBM50295572
(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8/h3-5,7,11-15H,6H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibitory affect against rabbit thymus thymidine kinase and represented as molt/4F kinase. |
Drug Metab Dispos 40: 2332-41 (2012)
Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M |
More data for this Ligand-Target Pair | |
ADRB2
(BOVINE) | BDBM50295572
(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8/h3-5,7,11-15H,6H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | 9.12E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA) |
J Med Chem 28: 1328-34 (1985)
BindingDB Entry DOI: 10.7270/Q2HX1DZG |
More data for this Ligand-Target Pair | |