BindingDB logo
myBDB logout

null

SMILES: CN1CCC(CC1)N1CCN(CC1)C(=O)Cn1ccc(NC(=O)c2ccc(Cl)s2)n1

InChI Key: InChIKey=FODZBIQMIDXVAY-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295580   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50295580
PNG
(4-chloro-N-(1-(2-(4-(1-methylpiperidin-4-yl)pipera...)
Show SMILES CN1CCC(CC1)N1CCN(CC1)C(=O)Cn1ccc(NC(=O)c2ccc(Cl)s2)n1
Show InChI InChI=1S/C20H27ClN6O2S/c1-24-7-4-15(5-8-24)25-10-12-26(13-11-25)19(28)14-27-9-6-18(23-27)22-20(29)16-2-3-17(21)30-16/h2-3,6,9,15H,4-5,7-8,10-14H2,1H3,(H,22,23,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
 74n/an/an/an/an/an/an/an/a



F Hoffmann - La Roche Ltd

Curated by ChEMBL


Assay Description
Binding affinity to factor 10a

Eur J Med Chem 44: 2787-95 (2009)


Article DOI: 10.1016/j.ejmech.2008.12.025
BindingDB Entry DOI: 10.7270/Q2CV4HSP
More data for this
Ligand-Target Pair