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SMILES: Fc1cc(ccc1NC(=O)Cn1nnc(NC(=O)c2ccc(Cl)s2)n1)-n1ccccc1=O

InChI Key: InChIKey=WDQYHPMZCRLJPH-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295584   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50295584
PNG
(4-chloro-N-(2-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-y...)
Show SMILES Fc1cc(ccc1NC(=O)Cn1nnc(NC(=O)c2ccc(Cl)s2)n1)-n1ccccc1=O
Show InChI InChI=1S/C19H13ClFN7O3S/c20-15-7-6-14(32-15)18(31)23-19-24-26-28(25-19)10-16(29)22-13-5-4-11(9-12(13)21)27-8-2-1-3-17(27)30/h1-9H,10H2,(H,22,29)(H,23,25,31)
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MMDB

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 11n/an/an/an/an/an/an/an/a



F Hoffmann - La Roche Ltd

Curated by ChEMBL


Assay Description
Binding affinity to factor 10a

Eur J Med Chem 44: 2787-95 (2009)


Article DOI: 10.1016/j.ejmech.2008.12.025
BindingDB Entry DOI: 10.7270/Q2CV4HSP
More data for this
Ligand-Target Pair