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SMILES: CC(C)N(CC(O)CO\N=C(/Cl)c1nc2ccccc2o1)C(C)(C)C

InChI Key: InChIKey=KOMLXORCKPICOD-PGMHBOJBSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295781   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Heat shock factor protein 1


(Homo sapiens (Human))		BDBM50295781
PNG
(CHEMBL554525 | N-(3-(tert-butyl(isopropyl)amino)-2...)
Show SMILES CC(C)N(CC(O)CO\N=C(/Cl)c1nc2ccccc2o1)C(C)(C)C
Show InChI InChI=1S/C18H26ClN3O3/c1-12(2)22(18(3,4)5)10-13(23)11-24-21-16(19)17-20-14-8-6-7-9-15(14)25-17/h6-9,12-13,23H,10-11H2,1-5H3/b21-16-
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Article
PubMed
n/an/an/an/a 1.66E+4n/an/an/an/a



CytRx Corporation

Curated by ChEMBL


Assay Description
Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...

Bioorg Med Chem Lett 19: 3128-35 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.011
BindingDB Entry DOI: 10.7270/Q23B605H
More data for this
Ligand-Target Pair