BDBM50295795 5-(ethylsulfonyl)-N-(2-hydroxy-3-(piperidin-1-yl)propoxy)benzo[d]oxazole-2-carbimidoyl chloride::CHEMBL561378

SMILES: CCS(=O)(=O)c1ccc2oc(nc2c1)C(\Cl)=N\OCC(O)CN1CCCCC1

InChI Key: InChIKey=ZVEMONMPKSDWSS-FXBPSFAMSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock factor protein 1 (Homo sapiens (Human))	BDBM50295795 (5-(ethylsulfonyl)-N-(2-hydroxy-3-(piperidin-1-yl)p...) Show SMILES CCS(=O)(=O)c1ccc2oc(nc2c1)C(\Cl)=N\OCC(O)CN1CCCCC1 Show InChI InChI=1S/C18H24ClN3O5S/c1-2-28(24,25)14-6-7-16-15(10-14)20-18(27-16)17(19)21-26-12-13(23)11-22-8-4-3-5-9-22/h6-7,10,13,23H,2-5,8-9,11-12H2,1H3/b21-17-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.29E+4	n/a	n/a	n/a	n/a
CytRx Corporation Curated by ChEMBL					Assay Description Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...				Bioorg Med Chem Lett 19: 3128-35 (2009) Article DOI: 10.1016/j.bmcl.2009.03.011 BindingDB Entry DOI: 10.7270/Q23B605H
					More data for this Ligand-Target Pair