BDBM50295915 3-(6-Bromo-1-(3-(dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-pyrrolo[3,2-b]pyridin-1-yl)-1H-pyrrole-2,5-dione::CHEMBL562814

SMILES: CN(C)CCCn1cc(C2=C(C(=O)NC2=O)n2ccc3ncccc23)c2ccc(Br)cc12

InChI Key: InChIKey=NYWFJJLPHMRJFV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50295915 (3-(6-Bromo-1-(3-(dimethylamino)propyl)-1H-indol-3-...) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)n2ccc3ncccc23)c2ccc(Br)cc12 |t:9| Show InChI InChI=1S/C24H22BrN5O2/c1-28(2)10-4-11-29-14-17(16-7-6-15(25)13-20(16)29)21-22(24(32)27-23(21)31)30-12-8-18-19(30)5-3-9-26-18/h3,5-9,12-14H,4,10-11H2,1-2H3,(H,27,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-GSK3beta expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 17: 4302-12 (2009) Article DOI: 10.1016/j.bmc.2009.05.031 BindingDB Entry DOI: 10.7270/Q2XP750M
					More data for this Ligand-Target Pair