BDBM50296057 1-ethyl-6-methyl-3-(1H-pyrrol-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione::CHEMBL541255

SMILES: CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccc[nH]1

InChI Key: InChIKey=AWVABKDLGNOOSR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock factor protein 1 (Homo sapiens (Human))	BDBM50296057 (1-ethyl-6-methyl-3-(1H-pyrrol-2-yl)pyrimido[5,4-e]...) Show SMILES CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccc[nH]1 Show InChI InChI=1S/C12H12N6O2/c1-3-18-10-8(11(19)17(2)12(20)15-10)14-9(16-18)7-5-4-6-13-7/h4-6,13H,3H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a
CytRx Corporation Curated by ChEMBL					Assay Description Amplification of HSF1 transcriptional activity in human heat shock-induced HeLa cells assessed as granule formation treated 1 hr before heat shock ch...				Bioorg Med Chem Lett 19: 4303-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.073 BindingDB Entry DOI: 10.7270/Q2HD7VPC
					More data for this Ligand-Target Pair