BDBM50296251 4-(5-bromo-4-(prop-2-ynylamino)pyrimidin-2-ylamino)benzenesulfonamide::CHEMBL549757

SMILES: NS(=O)(=O)c1ccc(Nc2ncc(Br)c(NCC#C)n2)cc1

InChI Key: InChIKey=HBITXFFJRLBCBB-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50296251 (4-(5-bromo-4-(prop-2-ynylamino)pyrimidin-2-ylamino...) Show SMILES NS(=O)(=O)c1ccc(Nc2ncc(Br)c(NCC#C)n2)cc1 Show InChI InChI=1S/C13H12BrN5O2S/c1-2-7-16-12-11(14)8-17-13(19-12)18-9-3-5-10(6-4-9)22(15,20)21/h1,3-6,8H,7H2,(H2,15,20,21)(H2,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	331	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere and Tampere University Hospital Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assay				Bioorg Med Chem Lett 19: 4102-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.002 BindingDB Entry DOI: 10.7270/Q23778S7
					More data for this Ligand-Target Pair